Water-soluble · carboxylases
A coenzyme for enzymes that process fats, carbohydrates and amino acids. Popular for hair and nails, but evidence there is thin.
Helps carboxylase enzymes in fatty-acid synthesis, glucose production and amino-acid breakdown.
Liver and every cell's mitochondria.
Eggs (cooked), organ meats, salmon, seeds, nuts, sweet potato.
Adequate Intake: 30 mcg for adults. No upper limit set.
Rare; can cause hair thinning and scaly rash. Regularly eating raw egg whites can block biotin absorption.
No toxicity known, but high-dose supplements can make some lab tests wrong (including thyroid and heart tests). Tell your clinician if you take them.
Interferes with many lab tests that use biotin–streptavidin technology.
Evidence that biotin improves hair or nails in people without deficiency is limited.
General education only, not medical advice. Drafted Oct 2026 · pending qualified expert review.