Trace mineral
A cofactor for enzymes in bone formation, carbohydrate metabolism and antioxidant defense.
Activates enzymes including manganese superoxide dismutase, the main antioxidant enzyme in mitochondria.
Bone, liver, pancreas, mitochondria.
Whole grains, nuts, legumes, tea, leafy vegetables.
Adequate Intake: 2.3 mg (men), 1.8 mg (women). Upper limit: 11 mg.
Very rare.
Mostly occupational inhalation (welding, mining), which can cause nerve damage. Not a dietary concern for most people.
Iron and manganese compete for absorption.
Roles established; route of exposure matters a lot — a hazard-vs-risk example.
General education only, not medical advice. Drafted Oct 2026 · pending qualified expert review.