A molecule behaves the same whether it was made in a plant or a factory. Safety depends on the substance, dose and exposure — not its origin story.
Examples
Vitamin C from a lab is identical to vitamin C from an orange. Arsenic, botulinum toxin and poison ivy are all natural.
'Chemical-free'
Everything — including water and you — is made of chemicals.
'Clean'
There's no regulated definition of 'clean' beauty or 'clean' food.
Evidence & sources
'Natural' does not necessarily mean safe; some natural products can cause harm or interact with medicines. Evidence: established. Known: Documented safety reports. Unknown: — Source: NIH National Center for Complementary and Integrative Health, Know the Science: 'Natural' Doesn't Necessarily Mean Safer, or Better (Current revision).