Essential polyunsaturated fats
A family of polyunsaturated fats. ALA is essential from plants; EPA and DHA come mainly from fish and algae.
Structural part of cell membranes — DHA is concentrated in the brain and retina. EPA and DHA are made into signaling molecules involved in inflammation.
Brain, eyes, heart, cell membranes.
EPA/DHA: salmon, sardines, mackerel, trout, algal oil. ALA: flaxseed, chia, walnuts, canola and soybean oil.
Adequate Intake for ALA: 1.6 g (men), 1.1 g (women). No official RDA for EPA/DHA; many guidelines suggest about two servings of fish a week.
Clinical deficiency is rare.
High-dose fish oil may increase bleeding risk and, in some trials, atrial fibrillation.
May add to blood-thinning medications.
Eating fish is associated with lower heart disease risk; trials of fish-oil supplements in the general population show mixed results.
General education only, not medical advice. Drafted Oct 2026 · pending qualified expert review.