Sucralose

Sweetener · E955

What is Sucralose, and why is it used?

About 600 times sweeter than sugar, made from sucrose. Mostly passes through the body unabsorbed.

How it works

Chlorine atoms replace three hydroxyl groups on sugar, so taste receptors detect it but enzymes don't break it down.

Evidence

Approved by FDA and EFSA. Research continues on effects on gut microbes and heated use; findings so far are mixed.

Evidence & sources

• FDA's ADI for sucralose is 5 mg/kg body weight per day. Evidence: regulatory. Known: Set after review of more than 110 studies. Unknown: Long-term microbiome effects. Source: US FDA, Aspartame and Other Sweeteners in Food (Current revision).

Connected topics

• Acceptable Daily Intake
• Added Sugars

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General education only, not medical advice. Drafted Oct 2026 · pending qualified expert review.